Mathematical Biology Seminar Abstract
Apr 22, 2016
Libin Rong
Oakland University, Department of Mathematics and Statistics
10:30 am in MSB 318

Virus and T cell dynamics in HIV-infected individuals

HIV infection is still a serious health problem in the world. Effective combination therapy can control viral replication but cannot eradicate the virus. Mathematical models, combined with experimental data, have provided important insights into HIV dynamics and immune responses. In this talk, I will present some recent work on modeling HIV infection and treatment, such as HIV latency and persistence, viral blips, virus dynamics under different drugs, treatment intensification with additional drugs, and the slow time scale of target cell depletion. These results improve our understanding of the virus and T cells dynamics in HIV-infected individuals.