| HIV infection is still a serious health problem in the
world. Effective combination therapy can control viral replication
but cannot eradicate the virus. Mathematical models, combined with
experimental data, have provided important insights into HIV
dynamics and immune responses. In this talk, I will present some
recent work on modeling HIV infection and treatment, such as HIV
latency and persistence, viral blips, virus dynamics under different
drugs, treatment intensification with additional drugs, and the slow
time scale of target cell depletion. These results improve our
understanding of the virus and T cells dynamics in HIV-infected
individuals. |